The Cocaine(COC) Drug Urine Test is a simple one step immunochromatographic assay for the rapid, qualitative detection of COC and primarily benzoylecgonine as metabolites in urine. The cutoff of the test is 300 ng/ml of COC. It is the same as the SAMHSA recommended assay cutoff.

EXPLANATION OF THE TEST

Cocaine, derived from the leaves of the coca plant, is a potent central nervous system stimulant and a local anesthetic. Cocaine induces euphoria, confidence and a sense of increased energy in the user; these psychological effects are accompanied by increased heart rate, dilation of the pupils, fever, tremors and sweating. Cocaine is used by smoking, intravenous, intranasal or oral administration, and excreted in the urine primarily as benzoylecgonine in a short time. Benzoylecgonine has a longer biological half-life (5-8 hours) than cocaine (0.5-1.5 hours) and can generally be detected for 24-80 hours after cocaine use or exposure.

The COC test is based on the principle of the highly specific immunochemical reactions between antigens and antibodies, which are used for the analysis of specific substances in biological fluids. The sensitivity of the test is 300 ng/ml of COC.