The Multi Drug 5 Drug Urine Multi-Line Screen Test is a simple one step immunochromatographic assay for the rapid, qualitative detection of cocaine, amphetamine, methamphetamines (ecstasy), opiates (heroin, morphine) and tetrahydrocannabinol (marijuana, hashish) drug testing in urine.

The cutoff of the test is:
300 ng/ml of COC,
1000 ng/ml of AMP,
1000 ng/ml of MET,
300 ng/ml of OPI and
50 ng/ml of THC

as the SAMHSA recommended cutoff for these tests are assays cutoff.

The Multi Drug 5 Drug Urine Multi-Line Screen Test are more convenient urine drug test, sharp lines, easy to use and read, less customer’s mistakes.

EXPLANATION OF THE TEST

COC derived from the leaves of the coca plant, is a potent central nervous system stimulant and a local anesthetic. Cocaine induces euphoria, confidence and a sense of increased energy in the user; these psychological effects are accompanied by increased heart rate, dilation of the pupils, fever, tremors and sweating. Cocaine is used by smoking, intravenous, intranasal or oral administration, and excreted in the urine primarily as benzoylecgonine in a short time. Benzoylecgonine has a longer biological half-life (5-8 hours) than cocaine (0.5-1.5 hours) and can generally be detected for 24-80 hours after cocaine use or exposure.

AMP is class of potent sympathomimetic agents with therapeutic applications. They are chemically related to the human body's natural catecholamine, epinephrine and norepinephrine. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. More acute responses produce anxiety, paranoia, hallucinations, and psychotic behavior. The effects of amphetamines generally last 2-4 hours following use, and the drug has a half-life of 4-24 hours in the body. About 30% of amphetamines are excreted in the urine in unchanged form, with the remainder as hydroxylated and deaminated derivatives.

MET is a potent sympathomimetic agent with therapeutic applications. The drug can be taken orally, injected, or inhaled. Acute higher doses lead to enhanced stimulation of the central nervous system and induce euphoria, alertness, reduced appetite, and a sense of increased energy and power. Cardiovascular responses to MET include increased blood pressure and cardiac arrhythmias. More acute responses include anxiety, paranoia, hallucinations, psychotic behavior, and eventually, depression and exhaustion. The effects of MET generally last 2-4 hours, and the drug has a half-life of 9-24 hours in the body. MET is excreted in the urine primarily as amphetamine and oxidized and deaminated derivatives. However, 10-20% of MET is excreted unchanged. Thus, the presence of the parent compound in the urine indicates MET use. MET is generally detectable in the urine for 3-5 days, depending on urine pH level.

Opioid analgesics comprise a large group of substances, which control pain by depressing the central nervous system. Morphine is the prototype compound of this group. Morphine is excreted in the urine primarily as morphine-3-glucuronide while smaller amounts are excreted as unchanged free morphine and other metabolites. It is also the major metabolic product of codeine and heroin. Morphine is delectable in the urine for several days after an opiate dose.

THC (9-tetrahydrocannabinol) is the primary active ingredient in cannabinoids (marijuana). When ingested or smoked, it produces euphoric effects. Users have impairment of short-term memory and THC use slows learning. Also, it may cause transient episodes of confusion, anxiety, or even frank toxic delirium. Long term, relatively heavy use may be associated with behavioral disorders. The peak effect of smoking THC occurs in 20-30 minutes and the duration is 90-120 minutes after one cigarette. Elevated levels of urinary metabolites are found within hours of exposure and remain detectable for 3-10 days after smoking. The main metabolite excreted in the urine is 11-nor- 9-tetrahydrocannabinol-9-carboxylic acid.